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Regulatory Circuits of the AAA+ Disaggregase Hsp104
Yeast Hsp104 is an AAA+ chaperone that rescues proteins from the aggregated state. Six protomers associate to form the functional hexamer. Each protomer contains two AAA+ modules, NBD1 and NBD2. Hsp104 converts energy provided by ATP into mechanical force used to thread polypeptides through its axia...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093873/ https://ncbi.nlm.nih.gov/pubmed/21454552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216176 |
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