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BAD Contributes to RAF-mediated Proliferation and Cooperates with B-RAF-V600E in Cancer Signaling

BAD (Bcl-2 antagonist of cell death) belongs to the proapoptotic BH3-only subfamily of Bcl-2 proteins. Physiological activity of BAD is highly controlled by phosphorylation. To further analyze the regulation of BAD function, we investigated the role of recently identified phosphorylation sites on BA...

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Detalhes bibliográficos
Main Authors: Polzien, Lisa, Baljuls, Angela, Albrecht, Marco, Hekman, Mirko, Rapp, Ulf R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093868/
https://ncbi.nlm.nih.gov/pubmed/21317286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177345
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