Derivatives of Rhodamine 19 as Mild Mitochondria-targeted Cationic Uncouplers

A limited decrease in mitochondrial membrane potential can be beneficial for cells, especially under some pathological conditions, suggesting that mild uncouplers (protonophores) causing such an effect are promising candidates for therapeutic uses. The great majority of protonophores are weak acids...

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Hauptverfasser: Antonenko, Yuri N., Avetisyan, Armine V., Cherepanov, Dmitry A., Knorre, Dmitry A., Korshunova, Galina A., Markova, Olga V., Ojovan, Silvia M., Perevoshchikova, Irina V., Pustovidko, Antonina V., Rokitskaya, Tatyana I., Severina, Inna I., Simonyan, Ruben A., Smirnova, Ekaterina A., Sobko, Alexander A., Sumbatyan, Natalia V., Severin, Fedor F., Skulachev, Vladimir P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Bioenergetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093858/
https://ncbi.nlm.nih.gov/pubmed/21454507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212837
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