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Evidence That the Histone Methyltransferase Dot1 Mediates Global Genomic Repair by Methylating Histone H3 on Lysine 79

Global genomic repair (GGR) and transcription coupled repair (TCR) are two pathways of nucleotide excision repair (NER) that differ in the damage recognition step. How NER factors, especially GGR factors, access DNA damage in the chromatin of eukaryotic cells has been poorly understood. Dot1, a hist...

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書目詳細資料
Main Authors: Tatum, Danielle, Li, Shisheng
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093827/
https://ncbi.nlm.nih.gov/pubmed/21460225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241570
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