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Evidence That the Histone Methyltransferase Dot1 Mediates Global Genomic Repair by Methylating Histone H3 on Lysine 79

Global genomic repair (GGR) and transcription coupled repair (TCR) are two pathways of nucleotide excision repair (NER) that differ in the damage recognition step. How NER factors, especially GGR factors, access DNA damage in the chromatin of eukaryotic cells has been poorly understood. Dot1, a hist...

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Detalhes bibliográficos
Main Authors: Tatum, Danielle, Li, Shisheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093827/
https://ncbi.nlm.nih.gov/pubmed/21460225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241570
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