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Evidence That the Histone Methyltransferase Dot1 Mediates Global Genomic Repair by Methylating Histone H3 on Lysine 79

Global genomic repair (GGR) and transcription coupled repair (TCR) are two pathways of nucleotide excision repair (NER) that differ in the damage recognition step. How NER factors, especially GGR factors, access DNA damage in the chromatin of eukaryotic cells has been poorly understood. Dot1, a hist...

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Détails bibliographiques
Auteurs principaux: Tatum, Danielle, Li, Shisheng
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093827/
https://ncbi.nlm.nih.gov/pubmed/21460225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241570
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