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Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma (CC) is a rare tumour with a dismal prognosis. As conventional medical management offers minimal survival benefit, surgery currently represents the only chance of cure. We evaluated DNA copy number (CN) alterations in CC to identify novel therapeutic targets. METHODS:...

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Главные авторы: McKay, Siobhan C, Unger, Kristian, Pericleous, Stephanos, Stamp, Gordon, Thomas, Gerry, Hutchins, Robert R, Spalding, Duncan R C
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093642/
https://ncbi.nlm.nih.gov/pubmed/21492330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1477-2574.2010.00286.x
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