Genetic Factors in the Pathogenesis of Cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma (CC) is increasing in incidence, but its pathogenesis remains poorly understood. Chronic inflammation of the bile duct and cholestasis are major risk factors, but most cases in the West are sporadic. Genetic polymorphisms in biliary transporter proteins have been impli...

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Detalhes bibliográficos
Main Authors: Wadsworth, Christopher A., Dixon, Peter H., Wong, Jason H., Chapman, Michael H., McKay, Siobhan C., Sharif, Amar, Spalding, Duncan R., Pereira, Stephen P., Thomas, Howard C., Taylor-Robinson, Simon D., Whittaker, John, Williamson, Catherine, Khan, Shahid A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Clinical Relevance of Genetic Variants
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696362/
https://ncbi.nlm.nih.gov/pubmed/21691113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324688
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