Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

BACKGROUND & AIMS: Cholangiocarcinoma is a heterogeneous disease with a poor outcome that accounts for 5%–10% of primary liver cancers. We characterized its genomic and genetic features and associated these with patient responses to therapy. METHODS: We profiled the transcriptomes from 104 surgi...

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Hauptverfasser: Andersen, Jesper B., Spee, Bart, Blechacz, Boris R., Avital, Itzhak, Komuta, Mina, Barbour, Andrew, Conner, Elizabeth A., Gillen, Matthew C., Roskams, Tania, Roberts, Lewis R., Factor, Valentina M., Thorgeirsson, Snorri S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413201/
https://ncbi.nlm.nih.gov/pubmed/22178589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.12.005
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