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Chromosomal Position Effects Are Linked to Sir2-Mediated Variation in Transcriptional Burst Size

Gene expression noise varies with genomic position and is a driving force in the evolution of chromosome organization. Nevertheless, position effects remain poorly characterized. Here, we present a systematic analysis of chromosomal position effects by characterizing single-cell gene expression from...

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Detalhes bibliográficos
Main Authors: Batenchuk, Cory, St-Pierre, Simon, Tepliakova, Lioudmila, Adiga, Samyuktha, Szuto, Anna, Kabbani, Nazir, Bell, John C., Baetz, Kristin, Kærn, Mads
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093560/
https://ncbi.nlm.nih.gov/pubmed/21575565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.021
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