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Identification of response-modulated genetic interactions by sensitivity-based epistatic analysis

BACKGROUND: High-throughput genomics has enabled the global mapping of genetic interactions based on the phenotypic impact of combinatorial genetic perturbations. An important next step is to understand how these networks are dynamically remodelled in response to environmental stimuli. Here, we repo...

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Detalhes bibliográficos
Main Authors: Batenchuk, Cory, Tepliakova, Lioudmila, Kærn, Mads
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996989/
https://ncbi.nlm.nih.gov/pubmed/20831804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-493
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