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Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation
Autophagy is a conserved cellular process to degrade and recycle cytoplasmic components. During autophagy, lysosomes fuse with an autophagosome to form an autolysosome. Sequestered components are degraded by lysosomal hydrolases and presumably released into the cytosol by lysosomal efflux permeases....
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093520/ https://ncbi.nlm.nih.gov/pubmed/21518918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013800108 |
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