Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation

Autophagy is a conserved cellular process to degrade and recycle cytoplasmic components. During autophagy, lysosomes fuse with an autophagosome to form an autolysosome. Sequestered components are degraded by lysosomal hydrolases and presumably released into the cytosol by lysosomal efflux permeases....

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Bibliographic Details
Main Authors: Rong, Yueguang, McPhee, Christina K., Deng, Shuangshen, Huang, Lei, Chen, Lilian, Liu, Mei, Tracy, Kirsten, Baehrecke, Eric H., Yu, Li, Lenardo, Michael J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093520/
https://ncbi.nlm.nih.gov/pubmed/21518918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013800108
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