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INHIBITION OF ANDROGEN RECEPTOR ACTIVITY BY HISTONE DEACETYLASE 4 THROUGH RECEPTOR SUMOYLATION

The transcriptional activity of the androgen receptor is regulated by both ligand binding and posttranslational modifications including acetylation and SUMOylation. Histone deacetylases are known to catalyze the removal of acetyl groups from both histones and non-histone proteins. In the present stu...

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Detalhes bibliográficos
Main Authors: Yang, Yonghua, Tse, Anfernee Kai-Wing, Li, Pengfei, Ma, Qiuping, Xiang, Shengyan, Nicosia, Santo V., Seto, Edward, Zhang, Xiaohong, Bai, Wenlong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093431/
https://ncbi.nlm.nih.gov/pubmed/21242980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.600
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