Contribution of Cytochrome P450 and ABCB1 Genetic Variability on Methadone Pharmacokinetics, Dose Requirements, and Response

Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. The aim of this study is to analyze methadone dosage in responder and no...

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Xehetasun bibliografikoak
Egile Nagusiak: Fonseca, Francina, de la Torre, Rafael, Díaz, Laura, Pastor, Antonio, Cuyàs, Elisabet, Pizarro, Nieves, Khymenets, Olha, Farré, Magí, Torrens, Marta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093392/
https://ncbi.nlm.nih.gov/pubmed/21589866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019527
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