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Quantitative Epistasis Analysis and Pathway Inference from Genetic Interaction Data
Inferring regulatory and metabolic network models from quantitative genetic interaction data remains a major challenge in systems biology. Here, we present a novel quantitative model for interpreting epistasis within pathways responding to an external signal. The model provides the basis of an exper...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093353/ https://ncbi.nlm.nih.gov/pubmed/21589890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002048 |
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