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Crystal structure of native Anopheles gambiae Serpin-2, a negative regulator of melanization in mosquitoes

Serpins are the dominant group of protease inhibitors in metazoans that control a wide variety of biological processes including major innate immune reactions. One of these inhibitors, SRPN2, controls melanization in mosquitoes – a powerful, arthropod-specific innate immune response. SRPN2 depletion...

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Bibliografiska uppgifter
Huvudupphovsmän: An, Chunju, Lovell, Scott, Kanost, Michael R., Battaile, Kevin P., Michel, Kristin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092802/
https://ncbi.nlm.nih.gov/pubmed/21465556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23002
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