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Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes

Melanization is an innate immune response in arthropods that encapsulates and kills invading pathogens. One of its rate-limiting steps is the activation of prophenoloxidase (PPO), which is controlled by an extracellular proteinase cascade and serpin inhibitors. The molecular composition of this syst...

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Main Authors: An, Chunju, Budd, Aidan, Kanost, Michael R., Michel, Kristin
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070200/
https://ncbi.nlm.nih.gov/pubmed/20953892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0543-z
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