Computational design of an endo-1,4-β-xylanase ligand binding site

The field of computational protein design has experienced important recent success. However, the de novo computational design of high-affinity protein–ligand interfaces is still largely an open challenge. Using the Rosetta program, we attempted the in silico design of a high-affinity protein interfa...

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Detaylı Bibliyografya
Asıl Yazarlar: Morin, Andrew, Kaufmann, Kristian W., Fortenberry, Carie, Harp, Joel M., Mizoue, Laura S., Meiler, Jens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2011
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092692/
https://ncbi.nlm.nih.gov/pubmed/21349882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzr006
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