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HP1α is not necessary for the structural maintenance of centromeric heterochromatin

Heterochromatin protein 1 (HP1) was discovered as a protein essential for maintaining the silent transcriptional status of genes located within or close to centromeric regions of Drosophila chromosomes. Mammals express three variants of HP1 and of these, HP1α is a direct homolog of Drosophila HP1. T...

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Autors principals: Velichko, Artem K, Kantidze, Omar L, Razin, Sergey V
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092686/
https://ncbi.nlm.nih.gov/pubmed/20962594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.3.13866
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