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Dual effect of heat shock on DNA replication and genome integrity
Heat shock (HS) is one of the better-studied exogenous stress factors. However, little is known about its effects on DNA integrity and the DNA replication process. In this study, we show that in G1 and G2 cells, HS induces a countable number of double-stranded breaks (DSBs) in the DNA that are marke...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431931/ https://ncbi.nlm.nih.gov/pubmed/22787276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1009 |
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