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Targeting the neurovascular unit for treatment of neurological disorders
Drug discovery for CNS disorders has been restricted by the inability for therapeutic agents to cross the blood-brain barrier (BBB). Moreover, current drugs aim to correct neuron cell signaling, thereby neglecting pathophysiological changes affecting other cell types of the neurovascular unit (NVU)....
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092634/ https://ncbi.nlm.nih.gov/pubmed/21172386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2010.12.004 |
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