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NOX2 inhibition with apocynin worsens stroke outcome in aged rats

BACKGROUND AND PURPOSE: This study utilized middle cerebral artery occlusion (MCAO) with tissue plasminogen activator (tPA) to assess inhibition of the NOX2 isoform of NADPH oxidase on brain injury and functional recovery in aged rats. METHODS: Effects of NOX2 on the degree of brain injury and funct...

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Detalhes bibliográficos
Main Authors: Kelly, Kimberly, Li, Xinlan, Tan, Zhenjun, VanGilder, Reyna, Rosen, Charles, Huber, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751637/
https://ncbi.nlm.nih.gov/pubmed/19635468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.052
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