Bryostatin improves survival and reduces ischemic brain injury in aged rats following acute ischemic stroke

BACKGROUND AND PURPOSE: Bryostatin, a potent protein kinase C (PKC) activator, has demonstrated therapeutic efficacy in preclinical models of associative memory, Alzheimer's disease, global ischemia, and traumatic brain injury. In this study, we tested the hypothesis that administration of bryo...

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Detalhes bibliográficos
Main Authors: Tan, Zhenjun, Turner, Ryan C., Leon, Rachel L., Li, Xinlan, Hongpaisan, Jarin, Zheng, Wen, Logsdon, Aric F., Naser, Zachary J., Alkon, Daniel L., Rosen, Charles L., Huber, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041549/
https://ncbi.nlm.nih.gov/pubmed/24172582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.002411
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