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Regulation of ATM/DNA-PKcs Phosphorylation by BRCA1-Associated BAAT1

BRCA1 has been implicated in the DNA damage pathway and regulation of genome stability, however, it does not contain intrinsic catalytic activity to repair the DNA lesions. Thus, a potential activity of BRCA1 is to assemble proteins that sense DNA damage and to transduce checkpoint signals to downst...

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Bibliographic Details
Main Authors: Ouchi, Mutsuko, Ouchi, Toru
Format: Artigo
Language:Inglês
Published: SAGE Publications 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092282/
https://ncbi.nlm.nih.gov/pubmed/21779444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911404222
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