The “Mutated in Colorectal Cancer” Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint

MCC is a potential tumor suppressor gene, which is silenced by promoter hypermethylation in a subset of colorectal cancers. However, its functions have remained poorly understood. In the present study, we describe a novel function of MCC in the DNA damage response. Several novel phosphorylation site...

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Main Authors: Pangon, Laurent, Sigglekow, Nicholas D., Larance, Mark, Al-Sohaily, Sam, Mladenova, Dessislava N., Selinger, Christina I., Musgrove, Elizabeth A., Kohonen-Corish, Maija R. J.
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2010
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092258/
https://ncbi.nlm.nih.gov/pubmed/21779472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910388937
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