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HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer
Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or as a result of inactivating mutations in negative re...
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| Main Authors: | , , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Company of Biologists
2015-09-01
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| 叢編: | Disease Models & Mechanisms |
| 主題: | |
| 在線閱讀: | http://dmm.biologists.org/content/8/9/1093 |
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