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HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer

Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or as a result of inactivating mutations in negative re...

詳細記述

保存先:
書誌詳細
主要な著者: Dessislava N. Mladenova, Jane E. Dahlstrom, Phuong N. Tran, Fahad Benthani, Elaine G. Bean, Irvin Ng, Laurent Pangon, Nicola Currey, Maija R. J. Kohonen-Corish
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015-09-01
シリーズ:Disease Models & Mechanisms
主題:
MIF
AHR
オンライン・アクセス:http://dmm.biologists.org/content/8/9/1093
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