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Overexpression of BH3-Only Protein BNIP3 Leads to Enhanced Tumor Growth

BCL-2/E1B-19 kDa–interacting protein 3 (BNIP3) is a BH3-only mitochondrial protein. Expression of BNIP3 is strongly stimulated by hypoxia. Up-regulation of BNIP3 has been detected in several human carcinomas including carcinomas of the lung and breast. The significance of BNIP3 overexpression in the...

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Detalhes bibliográficos
Main Authors: Vijayalingam, S., Pillai, Sreeraj G., Rashmi, Ramachandran, Subramanian, T., Sagartz, John E., Chinnadurai, G.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092255/
https://ncbi.nlm.nih.gov/pubmed/21779475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910386110
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