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Overexpression of BH3-Only Protein BNIP3 Leads to Enhanced Tumor Growth
BCL-2/E1B-19 kDa–interacting protein 3 (BNIP3) is a BH3-only mitochondrial protein. Expression of BNIP3 is strongly stimulated by hypoxia. Up-regulation of BNIP3 has been detected in several human carcinomas including carcinomas of the lung and breast. The significance of BNIP3 overexpression in the...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092255/ https://ncbi.nlm.nih.gov/pubmed/21779475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910386110 |
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