PI3K/Akt-Dependent Transcriptional Regulation and Activation of BMP-2-Smad Signaling by NF-κB in Metastatic Prostate Cancer Cells

BACKGROUND: Bone morphogenetic proteins (BMPs) exert osteoinductive effects in prostate cancer (PC) via uncharacterized mechanisms. In this study, we investigated whether the nuclear transcription factor NF-κB, implicated in PC metastasis, is involved in transcriptional regulation and activation of...

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Detalhes bibliográficos
Main Authors: Graham, Tisheeka R., Odero-Marah, Valerie A., Chung, Leland W., Agrawal, Krishna C., Davis, Rodney, Abdel-Mageed, Asim B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092122/
https://ncbi.nlm.nih.gov/pubmed/18942118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20870
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