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Detection of DNA fusion junctions for BCR-ABL translocations by Anchored ChromPET

Anchored ChromPET, a technique to capture and interrogate targeted sequences in the genome, has been developed to identify chromosomal aberrations and define breakpoints. Using this method, we could define the BCR-ABL1 translocation DNA breakpoint to a base-pair resolution in Philadelphia chromosome...

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Autors principals: Shibata, Yoshiyuki, Malhotra, Ankit, Dutta, Anindya
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092121/
https://ncbi.nlm.nih.gov/pubmed/20860819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm191
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