Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells

Non-small cell lung cancer (NSCLC) cells are often associated with constitutive activation of the phosphatidylinositol 3-kinase (PI3K)->Akt->mTOR pathway. The mucin 1 (MUC1) heterodimeric glycoprotein is aberrantly overexpressed in NSCLC and induces gene signatures that are associated with poo...

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Autors principals: Raina, Deepak, Kosugi, Michio, Ahmad, Rehan, Panchamoorthy, Govind, Rajabi, Hasan, Alam, Maroof, Shimamura, Takeshi, Shapiro, Geoffrey I., Supko, Jeffrey, Kharbanda, Surender, Kufe, Donald
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092019/
https://ncbi.nlm.nih.gov/pubmed/21421804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1050
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