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Quantitative sequence-activity models (QSAM)--tools for sequence design.

Models have been developed that allow the biological activity of a DNA segment to be altered in a desired direction. Partial least squares projections to latent structures (PLS) was used to establish a quantitative model between a numerical description of 68 bp fragments of 25 E.coli promoters and t...

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Détails bibliographiques
Auteurs principaux: Jonsson, J, Norberg, T, Carlsson, L, Gustafsson, C, Wold, S
Format: Artigo
Langue:Inglês
Publié: 1993
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC309176/
https://ncbi.nlm.nih.gov/pubmed/8441682
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