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Hybrid semiparametric systems for quantitative sequence-activity modeling of synthetic biological parts

Predicting the activity of modified biological parts is difficult due to the typically large size of nucleotide sequences, resulting in combinatorial designs that suffer from the “curse of dimensionality” problem. Mechanistic design methods are often limited by knowledge availability. Empirical meth...

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Detalhes bibliográficos
Publicado no:Synth Biol (Oxf)
Main Authors: Portela, Rui M C, von Stosch, Moritz, Oliveira, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513808/
https://ncbi.nlm.nih.gov/pubmed/32995518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/synbio/ysy010
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