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Quantitative sequence-activity models (QSAM)--tools for sequence design.
Models have been developed that allow the biological activity of a DNA segment to be altered in a desired direction. Partial least squares projections to latent structures (PLS) was used to establish a quantitative model between a numerical description of 68 bp fragments of 25 E.coli promoters and t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1993
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309176/ https://ncbi.nlm.nih.gov/pubmed/8441682 |
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