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Simplified Bacterial “Pore” Channel Provides Insight into the Assembly, Stability, and Structure of Sodium Channels

Eukaryotic sodium channels are important membrane proteins involved in ion permeation, homeostasis, and electrical signaling. They are long, multidomain proteins that do not express well in heterologous systems, and hence, structure/function and biochemical studies on purified sodium channel protein...

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Detalles Bibliográficos
Main Authors: McCusker, Emily C., D'Avanzo, Nazzareno, Nichols, Colin G., Wallace, B. A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091244/
https://ncbi.nlm.nih.gov/pubmed/21454659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.228122
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