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Heme Oxygenase-1 Couples Activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression

The induction of heme oxygenase-1 (HO-1; Hmox1) by inflammation, for instance in sepsis, is associated both with an anti-inflammatory response and with mitochondrial biogenesis. Here, we tested the idea that HO-1, acting through the Nfe2l2 (Nrf2) transcription factor, links anti-inflammatory cytokin...

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Autori principali: Piantadosi, Claude A., Withers, Crystal M., Bartz, Raquel R., MacGarvey, Nancy Chou, Fu, Ping, Sweeney, Timothy E., Welty-Wolf, Karen E., Suliman, Hagir B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091243/
https://ncbi.nlm.nih.gov/pubmed/21454555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207738
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