Co-regulation of nuclear respiratory factor-1 by NFκB and CREB links LPS-induced inflammation to mitochondrial biogenesis

The nuclear respiratory factor-1 (NRF1) gene is activated by lipopolysaccharide (LPS), which might reflect TLR4-mediated mitigation of cellular inflammatory damage via initiation of mitochondrial biogenesis. To test this hypothesis, we examined NRF1 promoter regulation by NFκB, and identified inters...

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Detaylı Bibliyografya
Asıl Yazarlar: Suliman, Hagir B., Sweeney, Timothy E., Withers, Crystal M., Piantadosi, Claude A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912462/
https://ncbi.nlm.nih.gov/pubmed/20587593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.064089
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