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Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice

Acute lung injury (ALI) initiates protective responses involving genes downstream of the Nrf2 (Nfe2l2) transcription factor, including heme oxygenase-1 (HO-1), which stimulates mitochondrial biogenesis and related anti-inflammatory processes. We examined mitochondrial biogenesis during Staphylococcu...

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Hlavní autoři: Athale, Janhavi, Ulrich, Allison, MacGarvey, Nancy Chou, Bartz, Raquel R., Welty-Wolf, Karen E., Suliman, Hagir B., Piantadosi, Claude A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729022/
https://ncbi.nlm.nih.gov/pubmed/22940620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.08.009
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