Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice

Acute lung injury (ALI) initiates protective responses involving genes downstream of the Nrf2 (Nfe2l2) transcription factor, including heme oxygenase-1 (HO-1), which stimulates mitochondrial biogenesis and related anti-inflammatory processes. We examined mitochondrial biogenesis during Staphylococcu...

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Bibliografiske detaljer
Main Authors: Athale, Janhavi, Ulrich, Allison, MacGarvey, Nancy Chou, Bartz, Raquel R., Welty-Wolf, Karen E., Suliman, Hagir B., Piantadosi, Claude A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729022/
https://ncbi.nlm.nih.gov/pubmed/22940620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.08.009
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