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Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice

Acute lung injury (ALI) initiates protective responses involving genes downstream of the Nrf2 (Nfe2l2) transcription factor, including heme oxygenase-1 (HO-1), which stimulates mitochondrial biogenesis and related anti-inflammatory processes. We examined mitochondrial biogenesis during Staphylococcu...

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Détails bibliographiques
Auteurs principaux: Athale, Janhavi, Ulrich, Allison, MacGarvey, Nancy Chou, Bartz, Raquel R., Welty-Wolf, Karen E., Suliman, Hagir B., Piantadosi, Claude A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729022/
https://ncbi.nlm.nih.gov/pubmed/22940620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.08.009
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