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Endosomal Targeting of the Phosphoinositide 3-Phosphatase MTMR2 Is Regulated by an N-terminal Phosphorylation Site

MTMR2 is a member of the myotubularin family of inositol lipid phosphatases, a large protein-tyrosine phosphatase subgroup that is conserved from yeast to humans. Furthermore, the peripheral neuromuscular disease Charcot-Marie Tooth disease type 4B has been attributed to mutations in the mtmr2 gene....

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Autors principals: Franklin, Norah E., Taylor, Gregory S., Vacratsis, Panayiotis O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091194/
https://ncbi.nlm.nih.gov/pubmed/21372139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.209122
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