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Human HEL308 Localizes to Damaged Replication Forks and Unwinds Lagging Strand Structures

HEL308 is a superfamily II DNA helicase, conserved from archaea through to humans. HEL308 family members were originally isolated by their similarity to the Drosophila melanogaster Mus308 protein, which contributes to the repair of replication-blocking lesions such as DNA interstrand cross-links. Bi...

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Autori principali: Tafel, Agnieszka A., Wu, Leonard, McHugh, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091193/
https://ncbi.nlm.nih.gov/pubmed/21398521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.228189
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