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Oxygen Binding and Redox Properties of the Heme in Soluble Guanylate Cyclase: IMPLICATIONS FOR THE MECHANISM OF LIGAND DISCRIMINATION
Soluble guanylate cyclase is an NO-sensing hemoprotein that serves as a NO receptor in NO-mediated signaling pathways. It has been believed that this enzyme displays no measurable affinity for O(2), thereby enabling the selective NO sensing in aerobic environments. Despite the physiological signific...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3091176/ https://ncbi.nlm.nih.gov/pubmed/21385878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177576 |
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