Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood

Enrichment of rare circulating tumor cells (CTCs) in blood is typically achieved using antibodies to epithelial cell adhesion molecule (EpCAM), with detection using cytokeratin (CK) antibodies. However, EpCAM and CK are not expressed in some tumors and can be downregulated during epithelial-to-mesen...

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Bibliografiske detaljer
Main Authors: Mikolajczyk, Stephen D., Millar, Lisa S., Tsinberg, Pavel, Coutts, Stephen M., Zomorrodi, Maryam, Pham, Tam, Bischoff, Farideh Z., Pircher, Tony J.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090615/
https://ncbi.nlm.nih.gov/pubmed/21577258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/252361
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