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Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies

The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics. Additionally, it has a potential role in sexual development and bile acid transport, and it is associated with a number of diseases, such as emphysema, spontaneous abortion, eclampsia and sever...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morisseau, Christophe, Bernay, Maud, Escaich, Aurélie, Sanborn, James R., Lango, Jozsef, Hammock, Bruce D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090455/
https://ncbi.nlm.nih.gov/pubmed/21371418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.02.038
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