The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol

Genome-wide association (GWA) studies represent a powerful strategy for identifying susceptibility genes for complex diseases in human populations but results must be confirmed and replicated. Because of the close homology between mouse and human genomes, the mouse can be used to add evidence to gen...

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Hlavní autoři: Leduc, Magalie S., Lyons, Malcolm, Darvishi, Katayoon, Walsh, Kenneth, Sheehan, Susan, Amend, Sarah, Cox, Allison, Orho-Melander, Marju, Kathiresan, Sekar, Paigen, Beverly, Korstanje, Ron
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2011
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090235/
https://ncbi.nlm.nih.gov/pubmed/21444760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M009175
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