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Combining QTL Data for HDL Cholesterol Levels from Two Different Species Leads to Smaller Confidence Intervals

QTL analysis detects regions of a genome that are linked to a complex trait. Once a QTL is detected, the region is narrowed via positional cloning in the hope of determining the underlying candidate gene – methods used include creating congenic strains, comparative genomics and gene expression analy...

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Hlavní autoři: Cox, A, Sheehan, SM, Klöting, I, Paigen, B, Korstanje, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958246/
https://ncbi.nlm.nih.gov/pubmed/20551980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2010.75
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