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The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex
The MRE11 complex (MRE11, RAD50 and NBS1) and the ataxia-telangiectasia mutated (ATM) kinase function in the same DNA damage response pathway to effect cell cycle checkpoint activation and apoptosis1–3. The functional interaction between the MRE11 complex and ATM has been proposed to require a conse...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089978/ https://ncbi.nlm.nih.gov/pubmed/17429352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05740 |
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