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The Mre11-Nbs1 interface is essential for viability and tumor suppression
The Mre11 complex (Mre11, Rad50 and Nbs1) is integral to both DNA repair and ATM-dependent DNA damage signaling. All three Mre11 complex components are essential for viability at the cellular and organismal level. To delineate essential and non-essential Mre11 complex functions that are mediated by...
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| Publicado en: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5234850/ https://ncbi.nlm.nih.gov/pubmed/28076792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.035 |
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