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In vivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory site

Current thinking suggests that despite the heterogeneity of myeloid-derived suppressor cells (MDSC), all Gr-1(+)CD11b(+) cells can become suppressive when exposed to inflammatory stimuli. In vitro evaluation shows MDSC from multiple tissue sites have suppressive activity, and in vivo inhibition of M...

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Bibliographic Details
Main Authors: Haverkamp, Jessica M., Crist, Scott A., Elzey, Bennett D., Cimen, Cansu, Ratliff, Timothy L.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089902/
https://ncbi.nlm.nih.gov/pubmed/21287554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041069
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