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Early Growth Response-1 (EGR-1) and Nuclear Factor of Activated T Cells (NFAT) Cooperate to Mediate CD40L Expression in Megakaryocytes and Platelets

Increasing evidence implicates circulating platelets as mediators of chronic inflammatory and autoimmune diseases via the expression and release of CD40L, an important modulator of inflammation and adaptive immune responses traditionally associated with activated T cells. Emerging evidence suggests...

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Detalhes bibliográficos
Main Authors: Crist, Scott A., Elzey, Bennett D., Ahmann, Michelle T., Ratliff, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837138/
https://ncbi.nlm.nih.gov/pubmed/24106272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511881
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