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Expression of Cationic Amino Acid Transporter 2 (CAT2) Is Required for Myeloid Derived Suppressor Cell-Mediated Control of T Cell Immunity
Myeloid derived suppressor cells (MDSC) are a heterogeneous population of immature cells that expand during benign and cancer-associated inflammation and are characterized by their ability to inhibit T cell immunity. Increased metabolism of L-Arginine, through the enzymes arginase 1 (ARG1) and nitri...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655170/ https://ncbi.nlm.nih.gov/pubmed/26491198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500959 |
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